Oncology-related research is of paramount importance. This research plays a pivotal role in advancing our understanding of cancer and identifying novel diagnostic and treatment tools to improve the lives of those affected. Cancer—in both prevalent and rare forms—remains one of the leading causes of death worldwide. The complexities of oncology present significant challenges to healthcare professionals. Through scientific inquiry and exploration, researchers can unravel the intricacies of cancer biology, discover new therapeutic targets, and improve existing treatments.
Dr. Daniel Herranz Benito, PhD, PharmD, of the Rutgers Cancer Institute of New Jersey, is one of the researchers working to transform our oncologic landscape. According to an announcement from the Rutgers Cancer Institute of New Jersey, Dr. Herranz Benito received $2.6 million in research grants to expand research into acute lymphoblastic leukemia (ALL). Acute lymphoblastic leukemia is an aggressive and rapidly progressing cancer that is most common in children; in adults, the cancer is often even more severe and associated with worse outcomes.
Dr. Herranz Benito received $1.8 million from the National Cancer Institute for a 5-year project and $800K from Alex’s Lemonade Stand Foundation for Childhood Cancer for a 4-year project. These projects will focus on whether pyruvate kinase inhibition could effectively treat pediatric or adult ALL alone or when used with other treatments.
Our Current Understanding of Acute Lymphoblastic Leukemia (ALL)
Acute lymphoblastic leukemia, which may also be referred to as acute lymphoid leukemia or acute lymphocytic leukemia, arises from immature blood cells called lymphocytes in the blood and bone marrow. These immature cells crowd out healthy blood cells, leading to characteristic symptoms. We know that bone marrow DNA errors cause ALL. However, scientists don’t quite know why these errors occur. Symptoms of acute lymphoblastic leukemia may include:
- Frequent nosebleeds
- Abnormal bleeding from the gums
- Recurrent infections
- Pallor (pale skin)
- Swollen lymph nodes
- Shortness of breath
- Easy bruising and bleeding
- Fatigue, weakness, and general malaise
- Bone pain
- Petechiae on the skin
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acute lymphoblastic leukemia leukemia oncology research grant
Last modified: February 20, 2024
